PAPERS PUBLISHED IN 2004
  This list is arranged by the name of the first author. Any omissions, mistakes and inconsistencies please communicate to the authors of compilation (m@5z.com). (If you are pointing to any reference, please use its ID# -- the last number in the reference.) You are welcome to use this compilation in your work. Proper way to quote it in your paper is: Lebl M.: Dynamic database of references in molecular diversity. Internet http://www.5z.com/divinfo.   
   Recently added entries are marked in bold 
 
- Adams,N., Arts,H.J., Bolton,P.D., Cowell,D., Dubberley,S.R., Friederichs,N., Grant,C.M., Kranenburg,M., Sealey,A.J., Wang,B., Wilson,P.J., Cowley,A.R., Mountford,P., & Schroeder,M. (2004)  Discovery and evaluation of highly active imidotitanium ethylene polymerisation catalysts using high throughput catalyst screening.  Chemical Communications (Cambridge, United Kingdom), 434-435. #20163 
- Akavia,A., Senderowitz,H., Lerner,A., & Shamir,R. (2004)  Designing a Multiroute Synthesis Scheme in Combinatorial Chemistry.  Journal of Combinatorial Chemistry,  6, 540-548. #20097 
- Amaya,T., Tanaka,H., & Takahashi,T. (2004)  Combinatorial synthesis of carbohydrate cluster on tree-type linker with orthogonally cleavable parts.  Synlett, 497-502. #20145 
- Anon. (2004)  Combinatorial chemistry-product focus.  Nature (London, United Kingdom),  430, No. #20037 
- Anon. (2004)  Analytical currents: combinatorial chemistry for biological targets.  Anal. Chem.,  76, 221A. #20059 
- Ansede,J.H., & Thakker,D.R. (2004)  High-throughput screening for stability and inhibitory activity of compounds toward cytochrome P450-mediated metabolism.  J. Pharm. Sci.,  93, 239-255. #20149 
- Apostolidis,A., Klimant,I., Andrzejewski,D., & Wolfbeis,O.S. (2004)  A Combinatorial Approach for Development of Materials for Optical Sensing of Gases.  Journal of Combinatorial Chemistry,  6, 325-331. #20160 
- Arakawa,M., & Funatsu,K. (2004)  Development of multi-dimensional data-modeling software.  Journal of Computer Chemistry, Japan,  3, 77-84. #20046 
- Arseniyadis,S., Wagner,A., & Mioskowski,C. (2004)  Resin-bound 4-phenyl-1,2-dihydroquinoline (DHQ): a new safety-catch linker for solid-phase organic synthesis (SPOS).  Tetrahedron Lett.,  45, 2251-2253. #20155 
- Arya,P., Wei,C.Q., Barnes,M.L., & Daroszewska,M. (2004)  A Solid Phase Library Synthesis of Hydroxyindoline-Derived Tricyclic Derivatives by Mitsunobu Approach.  Journal of Combinatorial Chemistry,  6, 65-72. #20180 
- Ayesa,S., Argyropoulos,D., Maltseva,T., Sund,C., & Samuelsson,B. (2004)  An expeditious library synthesis of N-monoalkylated aminopiperidines and -pyrrolidines.  Eur. J. Org. Chem., 2723-2737. #20056 
- Babine,R.E., Rynkiewicz,M.J., Jin,L., & Abdel-Meguid,S.S. (2004)  Towards an experimental de Novo design protocol. The use of protein crystallography to deconvolute dynamic combinatorial processes.  Letters in Drug Design & Discovery,  1, 173-177. #20102 
- Bao,Y., Li,C., Shen,H., & Nan,F. (2004)  Determination of Saikosaponin Derivatives in Radix bupleuri and in Pharmaceuticals of the Chinese Multiherb Remedy Xiaochaihu-tang Using Liquid Chromatographic Tandem Mass Spectrometry.  Anal. Chem.,  76, 4208-4216. #20088 
- Battersby, Bronwyn J., Grondahl, Lisbeth, Lawrie, Gwendolyn A., and Trau, Matt  Colloids for encoding chemical libraries: applications in biological screening. In: Anonymous.  (Eds.)  Colloids and Colloid Assemblies. #20448NEW
- Baurin,N., Baker,R., Richardson,C., Chen,I., Foloppe,N., Potter,A., Jordan,A., Roughley,S., Parratt,M., Greaney,P., Morley,D., & Hubbard,R.E. (2004)  Drug-like Annotation and Duplicate Analysis of a 23-Supplier Chemical Database Totaling 2.7 Million Compounds.  Journal of Chemical Information and Computer Sciences,  44, 643-651. #20162 
- Baytas,S.N., & Linhardt,R.J. (2004)  Combinatorial carbohydrate synthesis.  Mini-Reviews in Organic Chemistry,  1, 27-39. #20157 
- Berezin,V., & Bock,E. (2004)  NCAM mimetic peptides: Pharmacological and therapeutic potential.  Journal of Molecular Neuroscience,  22, 33-39. #20154 
- Bianchi,I., La Porta,E., Barlocco,D., & Raveglia,L.F. (2004)  Solid-Phase Convergent Synthesis of a Benzimidazolone Library via the Combination of Two Smaller Arrays of Carboxylic Acids and Secondary Amines.  Journal of Combinatorial Chemistry,  6, 835-845. #20040 
- Blake,J.F. (2004)  Integrating cheminformatic analysis in combinatorial chemistry.  Curr. Opin. Chem. Biol.,  8, 407-411. #20045 
- Boas,U., Gertz,H., Christensen,J.B., & Heegaard,P.M.H. (2004)  Facile synthesis of aliphatic isothiocyanates and thioureas on solid phase using peptide coupling reagents.  Tetrahedron Lett.,  45, 269-272. #20182 
- Bonaccurso,E., Butt,H.J., & Graf,K. (2004)  Microarrays by structured substrate swelling.  Eur. Polym. J.,  40, 975-980. #20115 
- Bork,J.T., Lee,J.W., & Chang,Y.T. (2004)  The combinatorial synthesis of purine, pyrimidine and triazine-based libraries.  QSAR & Combinatorial Science,  23, 245-260. #20064 
- Brown,J.X., Buckett,P.D., & Wessling-Resnick,M. (2004)  Identification of Small Molecule Inhibitors that Distinguish between Non-Transferrin Bound Iron Uptake and Transferrin-Mediated Iron Transport.  Chemistry & Biology,  11, 407-416. #20124 
- Buelow,A., Sinning,S., Wiborg,O., & Bols,M. (2004)  Two- and Three Dimensional Combinatorial Chemistry from Multicomponent Grignard Reagents.  Journal of Combinatorial Chemistry,  6, 509-519. #20108 
- Bugaut,A., Toulime,J.J., & Rayner,B. (2004)  Use of dynamic combinatorial chemistry for the identification of covalently appended residues that stabilize oligonucleotide complexes.  Angewandte Chemie, International Edition,  43, 3144-3147. #20061 
- Burke,M.D., & Schreiber,S.L. (2004)  A planning strategy for diversity-oriented synthesis.  Angewandte Chemie, International Edition,  43, 46-58. #20175 
- Byeon,W.H., & Weisblum,B. (2004)  Affinity adsorbent based on combinatorial phage display peptides that bind a-cobratoxin.  Journal of Chromatography, B: Analytical Technologies in the Biomedical and Life Sciences,  805, 361-363. #20104 
- Caturla,F., Enjo,J., Bernabeu,M.C., & Le Serre,S. (2004)  New fluorescent probes for testing combinatorial catalysts with phosphodiesterase and esterase activities.  Tetrahedron,  60, 1903-1911. #20455 
- Cavazzini,A., Massi,A., Bergamaschi,G., Braga,S., Dondi,F., & Dondoni,A. (2004)  Combining Synthetic and Analytical Strategies for Preparative HPLC Enantioseparation of Monastrol Racemic Mixture.  Biotechnol. Progr.,  20, 603-612. #20401 
- Cawse,J.N., Baerns,M., & Holena,M. (2004)  Efficient Discovery of Nonlinear Dependencies in a Combinatorial Catalyst Data Set.  Journal of Chemical Information and Computer Sciences,  44, 143-146. #20186 
- Chakraborty,T.K., Srinivasu,P., Tapadar,S., & Mohan,B.K. (2004)  Sugar amino acids and related molecules: Some recent developments.  Journal of Chemical Sciences (Bangalore, India),  116, 187-207. #20039 
- Chen,D., Hackbarth,C., Ni,Z.J., Wu,C., Wang,W., Jain,R., He,Y., Bracken,K., Weidmann,B., Patel,D.V., Trias,J., White,R.J., & Yuan,Z. (2004)  Peptide deformylase inhibitors as antibacterial agents: Identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach.  Antimicrob. Agents Chemother.,  48, 250-261. #20168 
- Chen,H., Li,Q., Yao,X., Fan,B., Yuan,S., Panaye,A., & Doucet,J.P. (2004)  CoMFA/CoMSIA/HQSAR and docking study of the binding mode of selective cyclooxygenase (COX-2) inhibitors.  QSAR & Combinatorial Science,  23, 36-55. #20132 
- Chen,L., Bao,J., Gao,C., Huang,S., Liu,C., & Liu,W. (2004)  Combinatorial Synthesis of Insoluble Oxide Library from Ultrafine/Nano Particle Suspension Using a Drop-on-Demand Inkjet Delivery System.  Journal of Combinatorial Chemistry,  6, 699-702. #20063 
- Chen,Y.T., & Seto,C.T. (2004)  Parallel synthesis of a library of bidentate protein tyrosine phosphatase inhibitors based on the a-ketoacid motif.  Bioorganic & Medicinal Chemistry,  12, 3289-3298. #20093 
- Cheng,C.W., Lin,K.C., Pan,F.M., Sinchaikul,S., Wong,C.H., Su,W.C., Hsu,C.H., & Chen,S.t. (2004)  Facile synthesis of metal-chelating peptides on chip for protein array.  Bioorganic & Medicinal Chemistry Letters,  14, 1987-1990. #20120 
- Christensen,C., Tornoe,C.W., & Meldal,M. (2004)  Pyrazines on solid support from peptides by periodinane oxidation of threonine side-chains. A quantitative chemical transformation (QCT) for combinatorial chemistry.  QSAR & Combinatorial Science,  23, 109-116. #20081 
- Cipolla,L. (2004)  Combinatorial libraries of biocatalysts: application and screening.  Comb. Chem. High Throughput Screening,  7, 101-114. #20110 
- Corbett,A.D., Cheeseman,J.D., Kazlauskas,R.J., & Gleason,J.L. (2004)  Pseudodynamic combinatorial libraries: A receptor-assisted approach for drug discovery.  Angew. Chem. Int. Ed.,  43, 2432-2436. #20028 
- Cozzi,P., Mongelli,N., & Suarato,A. (2004)  Recent anticancer cytotoxic agents.  Current Medicinal Chemistry: Anti-Cancer Agents,  4, 93-121. #20118 
- Cui,Z., Sun,L., & Zhang,B. (2004)  A peptidyl transferase ribozyme capable of combinatorial peptide synthesis.  Bioorganic & Medicinal Chemistry,  12, 927-933. #20150 
- de Graaf,K.L., Barth,S., Herrmann,M.M., Storch,M.K., Otto,C., Olsson,T., Melms,A., Jung,G., Wiesmueller,K.H., & Weissert,R. (2004)  MHC Class II Isotype- and Allele-Specific Attenuation of Experimental Autoimmune Encephalomyelitis.  Journal of Immunology,  173, 2792-2802. #20043 
- de la Hoz,A., Diaz-Ortiz,A., & Moreno,A. (2004)  Selectivity in organic synthesis under microwave irradiation.  Current Organic Chemistry,  8, 903-918. #20067 
- Delpiccolo,C.M.L., & Mata,E.G. (2004)  Efficient and selective solid-phase synthesis of trans 3-alkyl b-lactams from nonactivated acid chlorides.  Tetrahedron Lett.,  45, 4085-4088. #20106 
- Dikmans,A.J., Morr,M.Z.N., Adler,F., Turk,G., & Frank,R. (2004)  A new compact disc format of high density array synthesis applied to peptide nucleic acids and in situ MALDI analysis.  Mol. Diversity,  8, 197-207. #20025 
- Diness,F., Beyer,J., & Meldal,M. (2004)  Synthesis of 3-Boc-(1,3)-oxazinane-protected amino aldehydes from amino acids and their conversion into urea precursors. Novel building blocks for combinatorial synthesis.  QSAR & Combinatorial Science,  23, 130-144. #20080 
- Ding,K., Du,H., Yuan,Y., & Long,J. (2004)  Combinatorial chemistry approach to chiral catalyst engineering and screening: Rational design and serendipity.  Chemistry--A European Journal,  10, 2872-2884. #20057 
- Dong,Y., Roberge,J.Y., Wang,Z., Wang,X., Tamasi,J., Dell,V., Golla,R., Corte,J.R., Liu,Y., Fang,T., Anthony,M.N., Schnur,D.M., Agler,M.L., Dickson,J.K., Lawrence,R.M., Prack,M.M., Seethala,R., & Feyen,J.H.M. (2004)  Characterization of a new class of selective nonsteroidal progesterone receptor agonists.  Steroids,  69, 201-217. #20114 
- Edwards,A.A., Ichihara,O., Murfin,S., Wilkes,R., Whittaker,M., Watkin,D.J., & Fleet,G.W.J. (2004)  Tetrahydrofuran-Based Amino Acids as Library Scaffolds.  Journal of Combinatorial Chemistry,  6, 230-238. #20165 
- El Araby,M., Guo,H., Pottorf,R.S., & Player,M.R. (2004)  Solid-Phase Synthesis of an Alkylaminobenzanilide Library.  Journal of Combinatorial Chemistry,  6, 789-795. #20065 
- Erlanson,D.A., McDowell,R.S., & O'Brien,T. (2004)  Fragment-Based Drug Discovery.  J. Med. Chem.,  47, 3463-3482. #20082 
- Fechner,U., & Schneider,G. (2004)  Optimization of a pharmacophore-based correlation vector descriptor for similarity searching.  QSAR & Combinatorial Science,  23, 19-22. #20134 
- Fernandez,D., Ahaidar,A., Danelon,G., Cironi,P., Marfil,M., Perez,O., Cuevas,C., Albericio,F., Joule,J.A., & Alvarez,M. (2004)  Synthesis of Polyheterocyclic Nitrogen-Containing Marine Natural Products.  Monatshefte fuer Chemie,  135, 615-627. #20098 
- Fischer,P.M. (2004)  The design of drug candidate molecules as selective inhibitors of therapeutically relevant protein kinases.  Curr. Med. Chem.,  11, 1563-1583. #20089 
- Floriano,W.B., Vaidehi,N., Zamanakos,G., & Goddard,W.A., III. (2004)  HierVLS Hierarchical Docking Protocol for Virtual Ligand Screening of Large-Molecule Databases.  J. Med. Chem.,  47, 56-71. #20185 
- Fonseca,M.H., & List,B. (2004)  Combinatorial chemistry and high-throughput screening for the discovery of organocatalysts.  Curr. Opin. Chem. Biol.,  8, 319-326. #20071 
- Frantzen,A., Scheidtmann,J., Frenzer,G., Maier,W.F., Jockel,J., Brinz,T., Sanders,D., & Simon,U. (2004)  High-throughput method for the impedance spectroscopic characterization of resistive gas sensors.  Angewandte Chemie, International Edition,  43, 752-754. #20152 
- Fricker,P.C., Gastreich,M., & Rarey,M. (2004)  Automated Drawing of Structural Molecular Formulas under Constraints.  Journal of Chemical Information and Computer Sciences,  44, 1065-1078. #20113 
- Ganesan,A. (2004)  Combinatorial chemistry.  Curr. Opin. Chem. Biol.,  8, 209-210. #20077 
- Garbacia,S., Touzani,R., & Lavastre,O. (2004)  Image Analysis as a Quantitative Screening Test in Combinatorial Catalysis: Discovery of an Unexpected Ruthenium-Based Catalyst for the Sonogashira Reaction.  Journal of Combinatorial Chemistry,  6, 297-300. #20164 
- Garcia-Junceda,E., Garcia-Garcia,J.F., Bastida,A., & Fernandez-Mayoralas,A. (2004)  Enzymes in the synthesis of bioactive compounds: the prodigious decades.  Bioorganic & Medicinal Chemistry,  12, 1817-1834. #20125 
- Giacomelli,G., Porcheddu,A., & De Luca,L. (2004)  [1,3,5]-triazine: A versatile heterocycle in current applications of organic chemistry.  Current Organic Chemistry,  8, 1497-1519. #20031 
- Gil,C., Schwoegler,A., & Braese,S. (2004)  The Synthesis of 3-Substituted 6-Aryl-3 H-benzo[a][1,2,3]triazinones Using Polymer-Bound Triazenes.  Journal of Combinatorial Chemistry,  6, 38-42. #20183 
- Gilabert,M. (2004)  Combinatorial chemical paper in the drug discovery process.  Tecnicas de Laboratorio,  26, 140-143. #20398 
- Girard,C., Tranchant,I., Gorteau,V., Potey,L., & Herscovici,J. (2004)  Development of a DNA interaction test with small molecules still grafted on solid phase.  Journal of Combinatorial Chemistry,  6, 275-278. #20454 
- Gooding,O.W. (2004)  Process optimization using combinatorial design principles: parallel synthesis and design of experiment methods.  Curr. Opin. Chem. Biol.,  8, 297-304. #20399 
- Graham,D.J., Malarkey,C., & Schulmerich,M.V. (2004)  Information Content in Organic Molecules: Quantification and Statistical Structure via Brownian Processing.  Journal of Chemical Information and Computer Sciences,  44, 1601-1611. #20050 
- Graham,D.J., & Schulmerich,M.V. (2004)  Information Content in Organic Molecules: Reaction Pathway Analysis via Brownian Processing.  Journal of Chemical Information and Computer Sciences,  44, 1612-1622. #20049 
- Gros,P., Doudouh,A., & Fort,Y. (2004)  New polystyrene-supported stable source of 2-pyridylboron reagent for Suzuki couplings in combinatorial chemistry.  Tetrahedron Lett.,  45, 6239-6241. #20048 
- Hahn,H.G., Oh,H.S., Cheon,S.H., Oak,M.H., Kim,Y.R., & Kim,K.M. (2004)  Excavation of lead compounds that inhibit mast cell degranulation by combinatorial chemistry and activity-guided.  Archives of Pharmacal Research,  27, 518-523. #20066 
- Han,Y., Giroux,A., Grimm,E.L., Aspiotis,R., Francoeur,S., Bayly,C.I., McKay,D.J., Roy,S., Xanthoudakis,S., Vaillancourt,J.P., Rasper,D.M., Tam,J., Tawa,P., Thornberry,N.A., Paterson,E.P., Garcia-Calvo,M., Becker,J.W., Rotonda,J., Nicholson,D.W., & Zamboni,R.J. (2004)  Discovery of novel aspartyl ketone dipeptides as potent and selective caspase-3 inhibitors.  Bioorganic & Medicinal Chemistry Letters,  14, 805-808. #20169 
- Harper,G., Pickett,S.D., & Green,D.V.S. (2004)  Design of a compound screening collection for use in high throughput screening.  Comb. Chem. High Throughput Screening,  7, 63-71. #20126 
- Hattori,K., Kido,Y., Yamamoto,H., Ishida,J., Kamijo,K., Murano,K., Ohkubo,M., Kinoshita,T., Iwashita,A., Mihara,K., Yamazaki,S., Matsuoka,N., Teramura,Y., & Miyake,H. (2004)  Rational Approaches to Discovery of Orally Active and Brain-Penetrable Quinazolinone Inhibitors of Poly(ADP-ribose)polymerase.  J. Med. Chem.,  47, 4151-4154. #20053 
- Heeren,R.M.A., Kleinnijenhuis,A.J., McDonnell,L.A., & Mize,T.H. (2004)  A mini-review of mass spectrometry using high-performance FTICR-MS methods.  Analytical and Bioanalytical Chemistry,  378, 1048-1058. #20151 
- Hobbs,J.S., Simonian,M.H., Betgovargez,E., Ioffe,V., Movsisyan,A., Yu,J., James,C., & Bogler,O. (2004)  The fast and the curious: fragment-based lead discovery and optimization via high-throughput X-ray crystallography.  Mod. Drug Dis.,  7, 53-54, 56. #20069 
- Hou,T.J., Zhang,W., Xia,K., Qiao,X.B., & Xu,X.J. (2004)  ADME Evaluation in Drug Discovery. 5. Correlation of Caco-2 Permeation with Simple Molecular Properties.  Journal of Chemical Information and Computer Sciences,  44, 1585-1600. #20060 
- Houghten,R.A. Anonymous. (2004)  Silicagel-HF.  This Book.#20024 
- Houghten,R.A., Dooley,C.T., & Appel,J.R. (2004)  De novo identification of highly active fluorescent kappa opioid ligands from a rhodamine labeled tetrapeptide positional scanning library.  Bioorganic & Medicinal Chemistry Letters,  14, 1947-1951. #20121 
- Hu,Y., Nawoschik,K.J., Liao,Y., Ma,J., Fathi,R., & Yang,Z. (2004)  Synthesis of Conformationally Restricted 2,3-Diarylbenzo[b]furan by the Pd-Catalyzed Annulation of o-Alkynylphenols: Exploring a Combinatorial Approach.  J. Org. Chem.,  69, 2235-2239. #20139 
- Huenger,U., Ohnsmann,J., & Kunz,H. (2004)  Carbohydrate scaffolds for combinatorial syntheses that allow selective deprotection of all four positions independent of the sequence.  Angewandte Chemie, International Edition,  43, 1104-1107. #20137 
- Jensen,A.A., & Spalding,T.A. (2004)  Allosteric modulation of G-protein coupled receptors.  European Journal of Pharmaceutical Sciences,  21, 407-420. #20147 
- Ji,Y.F., Pan,X.D., & Wei,X.Y. (2004)  A solid-phase approach to fluorobenzimidazoles and fluoro-2-hydroxyquinoxalines using 'one-bead-two-compound' method.  Synlett, 1607-1609. #20437 
- Joensson,D., Warrington,B.H., & Ladlow,M. (2004)  Automated Flow-Through Synthesis of Heterocyclic Thioethers.  Journal of Combinatorial Chemistry,  6, 584-595. #20100 
- Juskowiak,G.L., Stachel,S.J., Tivitmahaisoon,P., & Van Vranken,D.L. (2004)  Fluorogenic Peptide Sequences - Transformation of Short Peptides into Fluorophores under Ambient Photooxidative Conditions.  J. Amer. Chem. Soc.,  126, 550-556. #20179 
- Kaempke,T. (2004)  Scalable distance similarity of chemical structures.  Comb. Chem. High Throughput Screening,  7, 11-21. #20127 
- Kam,Y.L., Rhee,S.J., & Choo,H.Y. (2004)  Solution-phase combinatorial synthesis of nonpeptide bradykinin antagonists.  Bioorganic & Medicinal Chemistry,  12, 3543-3552. #20079 
- Kenseth,J.R., He,Y., Tallman,D., Pang,H.m., & Coldiron,S.J. (2004)  Techniques for high-throughput characterization of peptides, oligonucleotides and catalysis efficiency.  Curr. Opin. Chem. Biol.,  8, 327-333. #20070 
- Knepper,K., Lormann,M.E.P., & Braese,S. (2004)  Efficient Synthesis of Highly Substituted Diaryl Ethers on Solid Supports Using the Ullmann Reaction.  Journal of Combinatorial Chemistry,  6, 460-463. #20109 
- Kohler,J.M., Henkel,T., Grodrian,A., Kirner,T., Roth,M., Martin,K., & Metze,J. (2004)  Digital reaction technology by micro segmented flow - components, concepts and applications.  Chemical Engineering Journal (Amsterdam, Netherlands),  101, 201-216. #20087 
- Koinuma,H., & Takeuchi,I. (2004)  Combinatorial solid-state chemistry of inorganic materials.  Nature Materials,  3, 429-438. #20396 
- Lai,G. (2004)  A convenient preparation of tetrahydrofuran-based diamines.  Syn. Commun.,  34, 1981-1987. #20062 
- Larsson,R., Pei,Z., & Ramstroem,O. (2004)  Catalytic self-screening of cholinesterase substrates from a dynamic combinatorial thioester library.  Angewandte Chemie, International Edition,  43, 3716-3718. #20047 
- Lavastre,O., Bonnette,F., & Gallard,L. (2004)  Parallel and combinatorial approaches for synthesis of ligands.  Curr. Opin. Chem. Biol.,  8, 311-318. #20072 
- Lee,H.K., & Rana,T.M. (2004)  Microwave-Assisted Parallel Synthesis of a 4,6-Diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine Library.  Journal of Combinatorial Chemistry,  6, 504-508. #20084 
- Lee,M.J., & Sun,C.M. (2004)  Traceless synthesis of hydantoin by focused microwave irradiation.  Tetrahedron Lett.,  45, 437-440. #20181 
- Lemmo,A.V., Hobbs,S., & Patel,P. (2004)  Micro Parallel Liquid Chromatography: Enabling Technology for Discovery Analytical Chemistry.  Assay and Drug Development Technologies,  2, 389-395. #20034 
- Leonard,J.T., & Roy,K. (2004)  Classical QSAR modeling of HIV-1 reverse transcriptase inhibitor 2-amino-6-arylsulfonylbenzonitriles and congeners.  QSAR & Combinatorial Science,  23, 23-35. #20133 
- Li,W., Chen,Y., & Lam,Y. (2004)  A facile solid-phase synthesis of 3,4,6-trisubstituted-2-pyridones using sodium benzenesulfinate as a traceless linker.  Tetrahedron Lett.,  45, 6545-6547. #20042 
- Lin,M.J., & Sun,C.M. (2004)  Focused microwave-assisted parallel synthesis of bis-benzimidazoles.  Synlett, 663-666. #20130 
- Lindsay,J.P., Clark,D.S., & Dordick,J.S. (2004)  Combinatorial formulation of biocatalyst preparations for increased activity in organic solvents: Salt activation of penicillin amidase.  Biotechnol. Bioeng.,  85, 553-560. #20143 
- Liu,R., Hsieh,C.Y., & Lam,K.S. (2004)  New approaches in identifying drugs to inactivate oncogene products.  Seminars in Cancer Biology,  14, 13-21. #20457 
- Ma,Y., Margarida,L., Brookes,J., Makara,G.M., & Berk,S.C. (2004)  Combinatorial Synthesis of Substituted Biaryls and Heterocyclic Arylamines.  Journal of Combinatorial Chemistry,  6, 426-430. #20123 
- Maclean,D., Holden,F., Davis,A.M., Scheuerman,R.A., Yanofsky,S., Holmes,C.P., Fitch,W.L., Tsutsui,K., Barrett,R.W., & Gallop,M.A. (2004)  Agonists of the Follicle Stimulating Hormone Receptor from an Encoded Thiazolidinone Library.  Journal of Combinatorial Chemistry,  6, 196-206. #20177 
- Maclean,D., & Martin,E.J. (2004)  On the representation of combinatorial libraries.  Journal of Combinatorial Chemistry,  6, 1-11. #20184 
- Maison,W., Grohs,D.C., & Prenzel,A.H.G.P. (2004)  Efficient synthesis of structurally diverse diazabicycloalkanes: scaffolds for modular dipeptide mimetics with tunable backbone conformations.  Eur. J. Org. Chem., 1527-1543. #20116 
- Maltais,R., Tremblay,M.R., Ciobanu,L.C., & Poirier,D. (2004)  Steroids and Combinatorial Chemistry.  Journal of Combinatorial Chemistry,  6, 443-456. #20101 
- Matikainen,J.K.T., & Elo,H.O. (2004)  A Novel Intramolecular Cyclization Reaction: Facile Solvent-Free Microscale Synthesis Suitable for Rapid Production of Libraries of 3-Amino-1,2,4-Triazines and for Combinatorial Chemistry.  Microchimica Acta,  146, 49-53. #20103 
- Matsuura,T., Ernst,A., Zechel,D.L., & Plueckthun,A. (2004)  Combinatorial approaches to novel proteins.  Chembiochem,  5, 177-182. #20148 
- McCarthy,J.F., Marx,K.A., Hoffman,P.E., Gee,A.G., O'Neil,P., Ujwal,M.L., & Hotchkiss,J. (2004)  Applications of machine learning and high-dimensional visualization in cancer detection, diagnosis, and management.  Annals of the New York Academy of Sciences,  1020, 239-262. #20054 
- Meier,M.A.R., Gohy,J.F., Fustin,C.A., & Schubert,U.S. (2004)  Combinatorial Synthesis of Star-Shaped Block Copolymers: Host-Guest Chemistry of Unimolecular Reversed Micelles.  J. Amer. Chem. Soc.,  126, 11517-11521. #20038 
- Mekenyan,O., Nikolova,N., Schmieder,P., & Veith,G. (2004)  COREPA-M: a multi-dimensional formulation of COREPA.  QSAR & Combinatorial Science,  23, 5-18. #20135 
- Meldal,M. (2004)  One bead two compound libraries' for detecting chemical and biochemical conversions.  Curr. Opin. Chem. Biol.,  8, 238-244. #20076 
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- Mitscher,L.A. (2004)  Analysis and Purification Methods in Combinatorial Chemistry, Edited by Bing Yang.  Journal of Natural Products,  67, 1076-1077. #20096 
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- Nefzi,A., Ostresh,J.M., Yu,Y., & Houghten,R.A. (2004)  Combinatorial Chemistry: Libraries from Libraries, the Art of the Diversity-Oriented Transformation of Resin-Bound Peptides and Chiral Polyamides to Low Molecular Weight Acyclic and Heterocyclic Compounds. [Vol. 69, 2004].  J. Org. Chem.,  69, 5516. #20055 
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- Oerfi,L., Waczek,F., Pato,J., Varga,I., Hegymegi-Barakonyi,B., Houghten,R.A., & Keri,G. (2004)  Improved, high yield synthesis of 3H-quinazolin-4-ones, the key intermediates of recently developed drugs.  Curr. Med. Chem.,  11, 2549-2553. #20029 
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- Ott,T., Kern,A., Schuffenhauer,A., Popov,M., Acklin,P., Jacoby,E., & Stoop,R. (2004)  Sequential Superparamagnetic Clustering for Unbiased Classification of High-Dimensional Chemical Data.  Journal of Chemical Information and Computer Sciences,  44, 1358-1364. #20083 
- Park,J.G., Langenwalter,K.J., Weinbaum,C.A., Casey,P.J., & Pang,Y.P. (2004)  Improved Loading and Cleavage Methods for Solid-Phase Synthesis Using Chlorotrityl Resins: Synthesis and Testing of a Library of 144 Discrete Chemicals as Potential Farnesyltransferase Inhibitors.  Journal of Combinatorial Chemistry,  6, 407-413. #20119 
- Parr,N.J., McKeown,S.C., Lindvall,M.K., Lorthioir,O.E., Congreve,M.S., & Watson,S.P. (2004)  The application of quantitative analytical constructs for chemistry optimization, monomer rehearsal and reactivity prediction in solid phase library synthesis.  Letters in Organic Chemistry,  1, 87-92. #20453 
- Patek,M., Safar,P., Smrcina,M., Wegrzyniak,E., Bjergarde,K., Weichsel,A., & Strop,P. (2004)  2D and 3D Spatially Addressed Arrays for High-Throughput Automated Synthesis of Combinatorial Libraries.  Journal of Combinatorial Chemistry,  6, 43-49. #20189 
- Petrenko,V.A., & Sorokulova,I.B. (2004)  Detection of biological threats. A challenge for directed molecular evolution.  J. Microbiol. Methods,  58, 147-168. #20058 
- Pirrung,M.C., & Das Sarma,K. (2004)  Multicomponent Reactions Are Accelerated in Water.  J. Amer. Chem. Soc.,  126, 444-445. #20178 
- Piscopio,A.D., & Robinson,J.E. (2004)  Recent applications of olefin metathesis to combinatorial chemistry.  Curr. Opin. Chem. Biol.,  8, 245-254. #20075 
- Porcheddu,A., Giacomelli,G., De Luca,L., & Ruda,A.M. (2004)  A \"Catch and Release\" Strategy for the Parallel Synthesis of 2,4,5-Trisubstituted Pyrimidines.  Journal of Combinatorial Chemistry,  6, 105-111. #20190 
- Prakash,G.K.S., & Etzkorn,M. (2004)  Direct oxidation of azides to nitro compounds.  Angewandte Chemie, International Edition,  43, 26-28. #20176 
- Rachakonda,S., & Cartee,L. (2004)  Challenges in antimicrobial drug discovery and the potential of nucleoside antibiotics.  Curr. Med. Chem.,  11, 775-793. #20128 
- Raghavendra,M.S., & Lam,Y. (2004)  Regiospecific solid-phase synthesis of substituted 1,2,3-triazoles.  Tetrahedron Lett.,  45, 6129-6132. #20051 
- Ralets,I., Ostergaard,S., Holm,A., Kohler,L., Bock,E., & Berezin,V. (2004)  Identification of neurite extension inducing peptides by means of soluble combinatorial peptide libraries.  J. Neurosci. Meth.,  137, 61-69. #20443 
- Ramstroem,O., Lohmann,S., Bunyapaiboonsri,T., & Lehn,J.M. (2004)  Dynamic combinatorial carbohydrate libraries: probing the binding site of the Concanavalin A lectin.  Chemistry--A European Journal,  10, 1711-1715. #20111 
- Richards,W.G., Grant,G.H., & Harrison,K.N. (2004)  Combating bioterrorism with personal computers.  Journal of Molecular Graphics & Modelling,  22, 473-478. #20078 
- Roque,A.C., Taipa,M.A., & Lowe,C.R. (2004)  A new method for the screening of solid-phase combinatorial libraries for affinity chromatography.  J. Mol. Recog.,  17, 262-267. #20086 
- Sanchez-Martin,R.M., Mittoo,S., & Bradley,M. (2004)  The impact of combinatorial methodologies on medicinal chemistry.  Current Topics in Medicinal Chemistry (Sharjah, United Arab Emirates),  4, 653-669. #20447 
- Savchuk,N.P., Balakin,K.V., & Tkachenko,S.E. (2004)  Exploring the chemogenomic knowledge space with annotated chemical libraries.  Curr. Opin. Chem. Biol.,  8, 412-417. #20044 
- Schimmer,A.D., Welsh,K., Pinilla,C., Wang,Z., Krajewska,M., Bonneau,M.J., Pedersen,I.M., Kitada,S., Scott,F.L., Bailly-Maitre,B., Glinsky,G., Scudiero,D., Sausville,E., Salvesen,G., Nefzi,A., Ostresh,J.M., Houghten,R.A., & Reed,J.C. (2004)  Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity.  Cancer Cell,  5, 25-35. #20158 
- Schmidt,F.R. (2004)  The challenge of multidrug resistance: actual strategies in the development of novel antibacterials.  Applied Microbiology and Biotechnology,  63, 335-343. #20174 
- Schwabacher,A.W., Johnson,C.W., & Geissinger,P. (2004)  Linear combinatorial synthesis with Fourier transform library analysis.  Macromolecular Rapid Communications,  25, 108-118. #20456 
- Sebestik,J., Matejka,P., Hlavacek,J., & Stibor,I. (2004)  Solid-phase synthesis of head and tail bis-acridinylated peptides.  Tetrahedron Lett.,  45, 1203-1205. #20170 
- Shannon,S.K., & Barany,G. (2004)  Colorimetric monitoring of solid-phase aldehydes using 2,4-dinitrophenylhydrazine.  Journal of Combinatorial Chemistry,  6, 165-170. #20161 
- Song,A., Zhang,J., & Lam,K.S. (2004)  Synthesis and Reactions of 7-Fluoro-4-methyl-6-nitro-2-oxo-2H-1-benzopyran-3-carboxylic Acid: A Novel Scaffold for Combinatorial Synthesis of Coumarins.  Journal of Combinatorial Chemistry,  6, 112-120. #20188 
- Song,A., Zhang,J., Lebrilla,C.B., & Lam,K.S. (2004)  Solid-Phase Synthesis and Spectral Properties of 2-Alkylthio-6H-pyrano[2,3-f]benzimidazole-6-ones: A Combinatorial Approach for 2-Alkylthioimidazocoumarins.  Journal of Combinatorial Chemistry,  6, 604-610. #20444 
- Song,A., Wang,X., Zhang,J., Marik,J., Lebrilla,C.B., & Lam,K.S. (2004)  Synthesis of hydrophilic and flexible linkers for peptide derivatization in solid phase.  Bioorganic & Medicinal Chemistry Letters,  14, 161-165. #20461 
- Song,A., Marik,J., & Lam,K.S. (2004)  Solid-phase synthesis of 3-alkyl-2-arylamino-3,4-dihydroquinazolines.  Tetrahedron Lett.,  45, 2727-2730. #20138 
- Song,Y., Yu,J., Li,Y., Li,G., & Xu,R. (2004)  Hydrogen-bonded helices in the layered aluminophosphate (C2H8N)2[Al2(HPO4)(PO4)2].  Angewandte Chemie, International Edition,  43, 399-2402. #20094 
- Spivey,A.C., Turner,D.J., Turner,M.L., & Yeates,S. (2004)  A tuneable Ge-based linker that enables application-led solid phase synthesis optimization - towards a robust iterative synthesis of oligothiophenes.  Synlett, 111-115. #20167 
- Srinivasan,N., & Kilburn,J.D. (2004)  Combinatorial approaches to synthetic receptors.  Curr. Opin. Chem. Biol.,  8, 305-310. #20073 
- Stock,N., & Bein,T. (2004)  High-throughput synthesis of phosphonate-based inorganic-organic hybrid compounds under hydrothermal conditions.  Angewandte Chemie, International Edition,  43, 749-752. #20153 
- Ternon,M., Diaz-Mochon,J.J., Belsom,A., & Bradley,M. (2004)  Dendrimers and combinatorial chemistry-tools for fluorescent enhancement in protease assays.  Tetrahedron,  60, 8721-8728. #20036 
- Tornoe,C.W., Sanderson,S.J., Mottram,J.C., Coombs,G.H., & Meldal,M. (2004)  Combinatorial Library of Peptidotriazoles: Identification of [1,2,3]-Triazole Inhibitors against a Recombinant Leishmania mexicana Cysteine Protease.  Journal of Combinatorial Chemistry,  6, 312-324. #20122 
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- Troitskaya,L.A., & Kodadek,T. (2004)  Peptides as modulators of enzymes and regulatory proteins.  Methods (San Diego, CA, United States),  32, 406-415. #20146 
- Tung,C.L., & Sun,C.M. (2004)  Liquid phase synthesis of chiral quinoxalinones by microwave irradiation.  Tetrahedron Lett.,  45, 1159-1162. #20171 
- Uttamchandani,M., Chen,G.Y.J., Lesaicherre,M.L., & Yao,S.Q. (2004)  Site-specific peptide immobilization strategies for the rapid detection of kinase activity on microarrays.  Methods in Molecular Biology (Totowa, NJ, United States),  264, 191-204. #20445 
- Vasilyev,V., & Bliznyuk,A. (2004)  Application of semiempirical quantum chemical methods as a scoring function in docking.  Theoretical Chemistry Accounts,  112, 313-317. #20033 
- Ventura,M., Farrell,W., Aurigemma,C., Tivel,K., Greig,M., Wheatley,J., Yanovsky,A., Milgram,K.E., Dalesandro,D., DeGuzman,R., Tran,P., Nguyen,L., Chung,L., Gron,O., & Koch,C.A. (2004)  High-throughput preparative process utilizing three complementary chromatographic purification technologies.  Journal of Chromatography, A,  1036, 7-13. #20112 
- Vess,C.J., Gilmore,J., Kohrt,N., & McGinn,P.J. (2004)  Combinatorial Synthesis of Oxide Powders with an Autopipetting System.  Journal of Combinatorial Chemistry,  6, 86-90. #20191 
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- Viljanen,J., Tegler,L., & Broo,K.S. (2004)  Combinatorial Chemical Reengineering of the Alpha Class Glutathione Transferases.  Bioconjug. Chem.,  15, 718-727. #20091 
- Villard,A.L., Warrington,B.H., & Ladlow,M. (2004)  A Fluorous-Tagged, Acid-Labile Protecting Group for the Synthesis of Carboxamides and Sulfonamides.  Journal of Combinatorial Chemistry,  6, 611-622. #20085 
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- Wang,G., De,J., Schoeniger,J.S., Roe,D.C., & Carbonell,R.G. (2004)  A hexamer peptide ligand that binds selectively to staphylococcal enterotoxin B: Isolation from a solid phase combinatorial library.  J. Pept. Res.,  64, 51-64. #20436 
- Wang,X., Zhang,J., Song,A., Lebrilla,C.B., & Lam,K.S. (2004)  Encoding method for OBOC small molecule libraries using a biphasic approach for ladder-synthesis of coding tags.  J. Amer. Chem. Soc.,  126, 5740-5749. #20446 
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- Watts,P., & Haswell,S.J. (2004)  Combinatorial synthesis in micro reactors.  Comb. Chem. High Throughput Screening,  7, 397-405. #20035 
- Wermuth,C.G. (2004)  Selective Optimization of Side Activities: Another Way for Drug Discovery.  J. Med. Chem.,  47, 1303-1314. #20159 
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- Wiczling,P., Markuszewski,M.J., & Kaliszan,R. (2004)  Determination of pKa by pH Gradient Reversed-Phase HPLC.  Anal. Chem.,  76, 3069-3077. #20107 
- Willand,N., Beghyn,T., Nowogrocki,G., Gesquiere,J.C., & Deprez,B. (2004)  Synthesis and structural studies of a novel scaffold for drug discovery: a 4,5-dihydro-3H-spiro[1,5-benzoxazepine-2,4'-piperidine].  Tetrahedron Lett.,  45, 1051-1054. #20173 
- Wittmann,V., & Seeberger,S. (2004)  Spatial screening of cyclic neoglycopeptides: Identification of polyvalent wheat-germ agglutinin ligands.  Angewandte Chemie, International Edition,  43, 900-903. #20452 
- Wu,X., Ding,S., Ding,Q., Gray,N.S., & Schultz,P.G. (2004)  Small molecules that induce cardiomyogenesis in embryonic stem cells.  J. Amer. Chem. Soc.,  126, 1590-1591. #20166 
- Xie,W., & Firestine,S.M. (2004)  A Simple, Inexpensive Reactor with Condenser for Use in Combinatorial Chemistry.  Journal of Combinatorial Chemistry,  6, 24-26. #20187 
- Xu,J., Szakal,C.W., Martin,S.E., Peterson,B.R., Wucher,A., & Winograd,N. (2004)  Molecule-Specific Imaging with Mass Spectrometry and a Buckminsterfullerene Probe: Application to Characterizing Solid-Phase Synthesized Combinatorial Libraries.  J. Amer. Chem. Soc.,  126, 3902-3909. #20140 
- Yan,B. (2004)  New combichem QC standards guard the supply of compounds and ensure HTS results.  Mod. Drug Dis.,  7, 30-32, 34. #20142 
- Yao,H., Costache,A.D., & Sem,D.S. (2004)  Chemical proteomic tool for ligand mapping of CYP antitargets: An NMR-compatible 3D QSAR descriptor in the heme-based coordinate system.  Journal of Chemical Information and Computer Sciences,  44, 1456-1465. #20090 
- Yao,N.H., He,W.Y., Lam,K.S., & Liu,G. (2004)  Solid-Phase Synthesis of O-Glycosylated Na-Fmoc Amino Acids and Analysis by High-Resolution Magic Angle Spinning NMR.  Journal of Combinatorial Chemistry,  6, 214-219. #20459 
- Yeh,W.B., & Sun,C.M. (2004)  Soluble polymer-supported synthesis of thioxotetrapyrimidinone by focused microwave irradiation.  Journal of Combinatorial Chemistry,  6, 279-282. #20172 
- Yeo,D.S.Y., Panicker,R.C., Tan,L.P., & Yao,S.Q. (2004)  Strategies for immobilization of biomolecules in a microarray.  Comb. Chem. High Throughput Screening,  7, 213-221. #20442 
- Yingyongnarongkul,B.E., Howarth,M., Elliott,T., & Bradley,M. (2004)  DNA transfection screening from single beads.  Journal of Combinatorial Chemistry,  6, 753-760. #20438 
- Young,S.S., & Ge,N. (2004)  Design of diversity and focused combinatorial libraries in drug discovery.  Current Opinion in Drug Discovery & Development,  7, 318-324. #20041 
- Zablotna,E., Dysasz,H., Lesner,A., Jaskiewicz,A., Kazmierczak,K., Miecznikowska,H., & Rolka,K. (2004)  A simple method for selection of trypsin chromogenic substrates using combinatorial chemistry approach.  Biochem. Biophys. Res. Commun.,  319, 185-188. #20092 
- Zajdel,P., Subra,G., Bojarski,A.J., Duszynska,B., Pawlowski,M., & Martinez,J. (2004)  A New Class of Arylpiperazine Derivatives: the Library Synthesis on SynPhase Lanterns and Biological Evaluation on Serotonin 5-HT1A and 5-HT2A Receptors.  Journal of Combinatorial Chemistry,  6, 761-767. #20068 
- Zaks-Makhina,E., Kim,Y., Aizenman,E., & Levitan,E.S. (2004)  Novel neuroprotective K+ channel inhibitor identified by high-throughput screening in yeast.  Mol. Pharmacol.,  65, 214-219. #20117 
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| Wednesday, September 29, 2004 |  |