Recent advances in solid phase synthesis
Steven E. Hall
Sphinx Pharmaceuticals, A Division of Eli Lilly, P.O. Box 13951, Research Triangle Park, NC 27709, U.S.A.
The use of solid phase synthesis continues to expand as chemists identify methodology that enables complex reactions. Recent efforts in this area have focused on new carbon-carbon bond forming reactions as well as a variety of heterocyclic systems. These examples are described along with updates on new linking strategies for solid phase synthesis.
bond forming reactions, function group conversion, heterocyclic synthesis, linker methodology, solid phase synthesis